Synvisc one injection are derivative of hyaluronan, a sodium salt of hyaluronic acid. Hyaluronan is a component of synovial fluid, a fluid responsible for viscosity in joints that helps in mobility. Synvisc one injection polymer A&B G-F 20 is given as an intra-articular injection for patients with knee osteoarthritis. It is used to decrease the pain and discomfort associated with knee disorders by acting as a temporary replacement of synovial fluid, which is helpful for patients who use the affected knee regularly. It may be used alone or in combination with other medicines. Do not consume this medication if you are allergic to Proteolytic or its ingredients.